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The Las Piñas General Hospital & Satellite Trauma Center (LPGH & STC), formerly called the Las Piñas Emergency Hospital was established in 1977 as an out-patient clinic located in front of the famous Las Piñas Bamboo Organ Church. It has been the only national government hospital in south Metro Manila. In 1984, the hospital was renamed as Las Piñas District Hospital (LPDH) and was integrated with the District Health Office IV under the National Capital Region, Department of Health (DOH), per Executive Order No. 119 of 1987.
On May 22, 1992, upon the approval of Republic Act No. 7539, the bed capacity of the hospital was increased from 25 to 50 beds. Through a series of department orders (DOH DO No. 456, s. 1994, and amended by DO No. 127-A, s. 1995), the DOH upgraded LPDH from a district hospital to a general hospital.
The LPDH was transferred to its new location in December 1997. It is now situated south of the National Capital Region, specifically at P. Diego Cera St., Bernabe Compound, Barangay Pulang Lupa I, Las Piñas City, serving the Muntiparlaspa cities (Muntinlupa, Parañaque, Las Piñas, and Pasay) and the cities of Bacoor and Imus and the neighboring towns of Cavite. In February 1999, the LPDH was chosen as the pilot and lead hospital for the implementation of the integration of public health services in the hospital, under the Integrated District Health System of the Department of Health, National Capital Region.